Aicar 50 mg: Unleash Endurance and Metabolic Efficiency
Dragon Pharma introduces Aicar 50 mg, a potent research peptide that has become a cornerstone for studies focused on metabolic enhancement and athletic performance. Known scientifically as AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), this compound works by activating the AMPK pathway, a key cellular energy sensor. For researchers and fitness enthusiasts exploring the frontiers of body composition, Dragon Pharma Aicar offers a unique mechanism to simulate the effects of endurance training and promote a leaner, more defined physique.
DRUG DESCRIPTION
Dragon Pharma’s Aicar is presented as a high-purity, sterile lyophilized powder in a convenient 50 mg / 2 mL vial. This formulation ensures stability and ease of reconstitution for laboratory use. The active substance, AICAR, is a nucleotide analog that mimics the effects of adenosine monophosphate (AMP). When introduced into a research model, it activates the AMP-activated protein kinase (AMPK) pathway. This “master metabolic switch” triggers a cascade of effects, including increased glucose uptake and fatty acid oxidation, while simultaneously decreasing the synthesis of fatty acids and cholesterol. Essentially, it signals the body to start burning stored fat for energy, making it a powerful tool for studying fat loss and endurance without the catabolic risks associated with intense calorie restriction.
AICAR PROFILE

Drug Class: Research Peptide
Main Active Substance: Aicar
Concentration: 50 mg/vial
Presentation: Lyophilized powder in 2 mL vial
Elimination Half-Life: ~6-8 hours
Recommended Dosage: Not established (research only)
Anabolic Ratio: N/A
Androgenic Ratio: N/A
Acne: No
Hepatotoxicity: Low
Aromatization: No
Manufacturer: Dragon Pharma
HOW TO USE AICAR
For research purposes, Aicar 50 mg is typically reconstituted with bacteriostatic water. Experimental protocols often involve daily administration, with research cycles lasting 4-8 weeks. Due to its relatively short half-life, splitting the dosage is common in advanced protocols. Aicar is frequently researched in combination with other compounds to create synergistic effects. For instance, stacking with GW501516 (Cardarine) is popular for dramatically enhancing endurance and fat oxidation. To build quality muscle in a caloric deficit, researchers often combine it with anabolic agents like Primobolan 100. For a powerful cutting stack, it can be paired with the beta-2 agonist Salbutamol. Post-research, a recovery protocol using a SERM such as Nolvadex is common to restore natural hormonal balance, especially when androgens are involved. Furthermore, peptides like BPC-157 may be incorporated into research to support joint and tendon health during intensive training phases.
POSSIBLE SIDE EFFECTS
In research settings, Aicar is generally well-tolerated, but some transient side effects have been observed. The most common reports include mild fatigue or tiredness, which is consistent with its energy-mimicking mechanism. Some subjects may experience a temporary decrease in blood glucose levels, underscoring the importance of monitoring. Unlike stimulant-based fat burners, Aicar does not cause jitters, anxiety, or increased heart rate, making it a subject of interest for those sensitive to such effects. As with any research compound, adherence to sterile techniques and proper dosing protocols is paramount to minimize risks.
CONCLUSION
Dragon Pharma’s Aicar 50 mg stands as a sophisticated and highly effective tool for metabolic and performance research. Its unique action on the AMPK pathway offers a non-stimulant approach to fat loss and endurance enhancement, making it a valuable asset for bodybuilders during cutting phases and athletes seeking a performance edge. When integrated into a well-designed research stack and coupled with a disciplined nutrition and training regimen, Aicar can contribute significantly to achieving a state of peak physical conditioning and superior vascularity.
AICAR FAQ
While Aicar is primarily researched for its endurance and fat-loss properties, it may have an anti-catabolic effect that helps preserve lean muscle tissue during a caloric deficit. For direct muscle growth, compounds like Testabol 400 are typically the focus of research.
The lyophilized powder should be reconstituted with bacteriostatic water. Gently swirl the vial until the contents are fully dissolved. Do not shake vigorously, as this can damage the peptide structure.
Aicar works by activating the AMPK pathway to increase fat burning and endurance, without being a stimulant. Clenbuterol is a beta-2 agonist that increases thermogenesis and metabolic rate, often causing stimulant-like side effects such as jitters and elevated heart rate.
Research cycles for Aicar typically range from 4 to 8 weeks. It is advisable to start with a shorter cycle to assess tolerance before committing to a longer duration. For detailed insights into metabolic pathways and AMPK activation, refer to this authoritative source: National Library of Medicine – AMPK Signaling.
In research models, administering Aicar 30-60 minutes before endurance-based activity has been shown to be effective. Its ability to enhance fatty acid oxidation can provide a steady stream of energy, making it ideal for long-duration, cardio-focused sessions.

